Lindsay O’Neill: The Wellness Hacker

Lindsay O’Neill is redefining what it means to take control of your health. As the Founder & CEO of Wellness Eternal and Small Hinges Health, she’s making biohacking both accessible and actionable—translating cutting-edge science into real-life habits that fuel energy, longevity, and performance. A TEDx and Gaia speaker, Harvard-certified Culinary Medicine Chef, and one of MSN’s Top 10 Notable Women of 2025, Lindsay is a force in the wellness world. After two decades in marketing media and technology, a traumatic accident while pregnant became the catalyst for a radical shift—from executive leadership to health transformation. 

Today, through her acclaimed Optimize W(e) podcast and the groundbreaking Biohacking Index, Lindsay is empowering individuals and practitioners with trusted, data-driven tools to optimize wellbeing from the inside out.

Lindsay, you’ve made a remarkable shift from a thriving career in AI and digital media to becoming a leader in wellness and longevity. What sparked this transformation, and how has your background shaped your approach?

My transformation was both urgent and deeply personal. After being hit by a car while pregnant, I was thrust into a world of unanswered questions—both my daughter and I were left with lingering health issues that traditional medicine simply couldn’t solve. That moment lit a fire in me. I didn’t want to manage symptoms, I wanted answers. So, I dove headfirst into the world of biohacking and integrative health, not as a hobbyist, but as a mother on a mission.

With a background in AI, media, and optimization strategy, I approached wellness like I would any data-driven system: test, measure, refine. I wasn’t interested in fluffy wellness trends, we needed results. That’s what led me to create the Biohacking Index, a transparent and trusted resource often called the “Yelp of Wellness,” where data, reviews, and science meet to cut through the noise.

Biohacking can seem overwhelming for beginners. How do you make longevity science simple and actionable?

I believe the future of health isn’t about overhauling everything—it’s about upgrading what’s already there. My mantra? Small hinges swing big doors. We start with diagnostics that reveal what your unique body needs, then we focus on four pillars: breath, sleep, hydration, and recovery. You don’t need 20 supplements and 5 hours a day… you need smart, strategic shifts.

At Wellness Eternal and Small Hinges Health, we make these changes simple and sustainable; like replacing coffee with hydrogen-rich water or stacking red light therapy into your existing morning routine. Through our Optimize W(e) Podcast and “entercational” platforms, we translate dense science into habits that fit real life. We also demystify cutting-edge biohacking solutions for healthcare practitioners so they can confidently share these tools—because when your doctor is on board, your healing accelerates.

You help people integrate wellness tools into their daily lives. What does that integration process look like, and how do you ensure it sticks?

Health doesn’t happen in a vacuum—it happens in your everyday choices. We focus on real-life integration: tools and habits that work with your schedule, not against it. We make health intuitive.

Our secret weapon? Entercation—education that feels entertaining. Whether through storytelling, events, online communities, or practitioner webinars, we design systems that people enjoy using. Because if something isn’t simple, effective, or even a little bit fun—it won’t stick.

You’ve spoken about AI-driven wellness. How do you see AI transforming health optimization in the next 5–10 years?

AI is the next frontier of personalized health. Today, it’s helping us interpret wearables and bloodwork. Tomorrow, it’ll be your proactive wellness coach—predicting stress patterns, recommending breathwork or supplements before you even know you need them.

At the Biohacking Index, we’re laying the groundwork now. By curating and vetting credible providers, modalities, and solutions, we’re preparing to integrate AI layers that can deliver actionable, personalized recommendations to both users and clinicians. The future of medicine is predictive, personalized, and AI-powered—and we’re helping lead that charge.

You often talk about energy and performance. What’s one underrated practice that can dramatically improve wellbeing?

Breathwork meets prayer. This combo is ancient, free, and massively effective. Five minutes a day of deep, intentional breathing—paired with meditation or prayer—can rebalance your nervous system, improve sleep, sharpen focus, and boost resilience.

If I could only choose one practice to recommend, this would be it. Stack it with resistance training, hydrogen water, and key supplements like C60 Power, methylated B9/B12, and D3+K2, and you’ve got a low-cost, high-impact vitality protocol that works across every age and lifestyle.

What’s your top advice for wellness entrepreneurs trying to scale while staying science-led?

Lead with truth and results. Use what you promote. Know the data. Don’t just ride the wellness wave—build something grounded, something credible.

Then, build systems. Educate your community. Automate where possible. And most importantly: become indispensable to your audience by solving their real problems. All business is a value exchange.

You don’t need millions of followers—you need loyal fans who trust you, learn from you, and share your work. That’s how you build a brand that doesn’t just trend—it lasts.

You were recently named one of MSN’s Top 10 Notable Women in 2025 and Top 30 in NY Weekly Magazine. What does that recognition mean to you?

It’s deeply humbling—but also incredibly motivating. That kind of recognition confirms that the mission behind Wellness Eternal is resonating: to cut through the noise and deliver truth, transparency, and transformation in a wellness industry that’s often clouded by hype.

But more than awards, I care about impact. I want to empower women to reclaim agency over their health, to stop outsourcing their wellbeing, and to become the CEOs of their own bodies. Recognition is beautiful. But transformation—that’s what fuels me every day.

You’ve teamed up with BIG media organizations (like Women’s Health Magazine, Forbes, Entrepreneur, and of course Global Woman’s Magazine) to provide Biohacking and Longevity truths to the masses. What is the focus of your articles?

I’m wildly passionate about making powerful health solutions accessible. That means featuring brands and providers who are truly changing lives—companies I personally use and trust, backed by clinical results, not just marketing buzz.

Through these features, I spotlight the innovators who are moving the needle in wellness and longevity. Then, I layer in Small Hinge Tips—tactical nutrition, recovery, and lifestyle hacks that help readers create big change through small, consistent steps.

The end goal? To equip every reader with tools that are science-backed, easy to adopt, and immediately effective. Because the future of wellness isn’t exclusive. It’s inclusive—and it starts with education.

You can explore more at www.wellnesseternal.com, www.biohackingindex.com and www.smallhinges.health.